Abstract: With the development of information technology, automation and intellectualization of distribution network, distribution network has gradually developed into a typical cyber physical system (CPS). In distribution network CPS, the information flow and energy flow is mixed, the discrete state and the continuous process interweave, and the dynamic process of conduction mechanism between cyber system and physical system are complex, these brings difficulty for distribution network CPS simulation. In this paper, the coupling relationship between physical system and cyber system in active distribution network CPS is analyzed. A distribution network communication service model based on IEC 61850 and multi-dimensional resolution model of distributed generations are constructed. A framework of information flow and energy flow fusion calculation is proposed, and a multi-rate cooperative timing simulation method based on trigger synchronization is adopted. A prototype system based on distribution network simulation module and OPNET is realized. The effectiveness and correctness of the model and algorithm are verified by a practical example from a CPS demonstration project.